zinc 2-amino-4-methylsulfanylbutanoic acid sulfate
Zinc methionine sulfate
CAS: 56329-42-1
Molecular Formula: C5H11NO6S2Zn
zinc 2-amino-4-methylsulfanylbutanoic acid sulfate - Names and Identifiers
| Name | Zinc methionine sulfate |
| Synonyms | OPTIZINC optizinc optizinc(TM) OPTIZINC(TM) Zinc methionate ZINC METHIONINE Zinc methionine ZINC MONOMETHIONINE Zinc monomethionine ZINC METHIONINE SULFATE Zinc methionine sulfate Zincmonomethionine,power Zinc methionine bisulfate Zinc monomethionine sulfate zinc 2-amino-4-methylsulfanylbutanoic acid sulfate Hydrogen (L-methioninato-N,O,S)(sulphato(2-)-O)zincate(1-) hydrogen (CL-methioninato-N,O,S)[sulphato(2-)-O]zincate(1-) Zincate(1-), (L-methioninato-.kappa.N,.kappa.O,.kappa.S)sulfato(2-)-.kappa.O-, hydrogen, (T-4)- |
| CAS | 56329-42-1 |
| EINECS | 260-113-8 |
| InChI | InChI=1/C5H11NO2S.H2O4S.Zn/c1-9-3-2-4(6)5(7)8;1-5(2,3)4;/h4H,2-3,6H2,1H3,(H,7,8);(H2,1,2,3,4);/q;;+2/p-2 |
zinc 2-amino-4-methylsulfanylbutanoic acid sulfate - Physico-chemical Properties
| Molecular Formula | C5H11NO6S2Zn |
| Molar Mass | 310.66 |
| Boling Point | 306.9°C at 760 mmHg |
| Flash Point | 139.4°C |
| Vapor Presure | 0.00017mmHg at 25°C |
| Storage Condition | Inert atmosphere,Room Temperature |
| Physical and Chemical Properties | White powder, soluble in water. |
| Use | Nutritional additives can be widely used in feed and food industry. |
zinc 2-amino-4-methylsulfanylbutanoic acid sulfate - Reference Information
| feed additive | zinc is one of the essential trace elements in animal body, which is the composition of a variety of metal enzymes and insulin. It has a wide range of physiological and biochemical functions in the body and is called "life element". Zinc is a component of a variety of enzymes in livestock and poultry, which is of great significance to the normal growth and development, reproductive function, the development of the taste system and the normal function of the cardiovascular system play an important role in the maintenance of fur growth, skin health and tissue repair essential elements. Zinc can also affect the synthesis of DNA, RNA, involved in the metabolism of nucleic acids and proteins. When zinc deficiency occurs, the animals develop skin incomplete keratinization, loss of appetite, incomplete embryonic development, decreased reproductive function, growth arrest and abnormal metabolism of epithelial cells, and lead to low immune function of livestock and poultry, increased susceptibility to disease, affecting the growth and development of livestock and poultry and feed utilization. In traditional feeding, zinc in animal diets is provided in the form of inorganic salts. In recent years, the application of adding organic zinc and Chelated zinc is increasingly widespread, and Zinc methionine is a zinc salt of methionine, it is a new feed additive, which can be used as a supplement of trace element zinc in animals. Many reports have confirmed that adding Zinc methionine can improve animal growth, reproduction and health, and promote the rapid proliferation of tongue mucosa taste bud cells, regulate appetite, inhibit some harmful bacteria in the intestine, prolong the residence time of food in the digestive tract, improve the secretion function of digestive system and the activity of enzymes in tissue cells. The absorption rate of Zinc methionine in animals is 2-4 times that of ordinary inorganic zinc, and methionine itself is also a higher nutrient. Human and animal can absorb zinc while absorbing methionine. |
| Application in animals | 1. Effects on chickens: under the condition of intensive production, organic zinc can improve the immune function of chickens. The 120-day-old Turkey fed with Zinc methionine and manganese methionine has improved the feed conversion rate, Mortality Rate% and foot deformity rate. The same feeding Zinc methionine and manganese methionine 45-day-old broilers, feed conversion rate, breast meat, bone ash content and skin damage were also significantly improved. 2. Effects on pigs: The nutritional effects of zinc on pigs are mainly in the following aspects: effects on the synthesis and activity of enzymes in pigs, the relationship between substance metabolism and growth; Effects on reproduction and immunity of pigs. According to the study, Zinc methionine on the above several aspects have different degrees of improvement. Adding Zinc methionine in finishing pig diets, the average daily gain increased by 9.7%, feed utilization rate increased by 3.3%, and the slaughter rate and lean meat percentage were increased. 3. Effect on rabbits: adding Zinc methionine to the diet of meat rabbits has obvious effect on weight gain. Zinc methionine chelate in the chemical structure of ionic bonds and coordination bonds coexist, has good chemical stability and biological stability. In the pH environment in the body, the solubility is good, easy to release zinc ions, so it is easy to be absorbed by the body, the absorption rate is 2 times to 3 times faster than that of inorganic zinc, and the biological effect is higher than that of inorganic salts. After feeding Zinc methionine, to meet the body's demand for zinc, zinc absorption in the body at the same time, methionine is also absorbed, so it can promote the growth and development of meat rabbits. The test shows that the appropriate dosage is about 50 mg/kg. According to another report, Zinc is an essential element for maintaining the optimal activity of mononuclear phagocytes (MNP), which can phagocytize pathogens. Therefore, zinc can affect the indirect defense system of meat rabbits and improve the immune function of rabbits, play a role in the prevention of epidemic disease. |
| method of use | pre-dilution was added to the feed and mixed. Its use object and dosage are shown in Figure 1. Figure 1 is the object and dosage of Zinc methionine. |
| preparation | A preparation method of Zinc methionine, comprising the following steps: (1) salt forming reaction step: to a 100 liter reactor with heating device, electric stirring and thermometer, 100 mol of methionine, 1500 mol of water, 55 mol of zinc oxide and 2 mol of formic acid were added, the reaction was carried out by heating at 70-80 ° C. While stirring, and the reaction was carried out for 6 hours under stirring. The heating was stopped, and the salt formation reaction was completed. (2) drying step: the granular product obtained by centrifugal separation is placed in the upper and lower air-permeable stainless steel drying sieves and dried in a drying oven; After 24 hours, the obtained product was sieved to obtain a Zinc methionine finished product having a zinc content of more than 15%. |
| note | excessive addition of this product will cause zinc poisoning. The maximum tolerance of animals to zinc (based on the diet): pigs, poultry 100mg/kg, cattle 500mg/kg, horse 500mg/kg, sheep 300mg/kg, rabbit 500mg/kg. Zinc and calcium, copper, iron and other elements have antagonistic effect, the content of these elements in the diet is higher, should be appropriate to increase the amount of zinc. |
| toxicity | can be used safely (FDA § 172.399,2000). |
| usage limit | GB 2760-2001: milk powder for children over one year old, 0.05-1.175g/kg. |
| Use | Nutrition Fortifier (zinc source). It is generally made into tablets. as a nutritional additive, can be used in food, feed, medicine and other industries nutritional additives, can be widely used in feed and food industry. |
| production method | zinc sulfate and DL-methionine at equal concentrations (mol/L) are reacted in pure water. |
Last Update：2024-04-09 15:16:51
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